Revision Applications for Mechanisms of Cancer Drug Resistance

These Funding Opportunity Announcements (FOA) are associated with the Cancer MoonshotSM Initiative that is intended to accelerate cancer research. Specifically, these FOAs target the following area designated as scientific priority by the Blue Ribbon Panel (BRP):

Recommendation C. Develop ways to overcome cancer’s resistance to therapy
Identify therapeutic targets to overcome drug resistance through studies that determine the mechanisms that lead cancer cells to become resistant to previously effective treatments.

The purpose of these FOAs are to support the addition of new aims and directions to ongoing NCI-funded grant portfolio on underlying mechanisms of resistance, preclinical design and foster development of single or combination therapies to effectively target resistant/refractory tumors and/or their microenvironment at the clinical level.

  • RFA-CA-19-049 Revision Applications for Mechanisms of Cancer Drug Resistance (R01 Clinical Trial Not Allowed)
  • RFA-CA-19-050 Revision Applications for Mechanisms of Cancer Drug Resistance (U01 Clinical Trial Not Allowed)
  • RFA-CA-19-051 Revision Applications for Mechanisms of Cancer Drug Resistance (U54 Clinical Trial Not Allowed)
  • RFA-CA-19-052 Revision Applications for Mechanisms of Cancer Drug Resistance (P01 Clinical Trial Not Allowed)
  • RFA-CA-19-053 Revision Applications for Mechanisms of Cancer Drug Resistance (P50 Clinical Trial Not Allowed)

The DRSN Steering Committee and Coordination Center will coordinate activities, and interactions between Investigators with Revision Application projects and the various DRSN-funded components. The detailed information of DRSN Revision Project awardees is available at DRSN members.